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BMS‑986490 Solid Tumors Study

Brief Summary

This is a study of BMS-986490 as a monotherapy and in combination with bevacizumab in participants with select advanced solid tumors known to express CEACAM5.

Official Title

A Phase 1/2a, Multicenter, Open‑Label, First in Human Study of BMS‑986490 With or Without Bevacizumab in Advanced Solid Tumors (NCT06730750)

Conditions

Advanced Solid Tumors

Cachexia (AV-380-25-301)

Brief Summary:

This is a randomized, double-blind Phase ⅔ study evaluating the effect of rilogrotug compared to placebo on weight gain and improvement in patient-reported anorexia.

Study Title:

A Randomized, Double-Blind, Phase 2/3 Study of Rilogrotug (AV-380) Versus Placebo in the Treatment of Anorexia and Weight Loss in Patients with Cancer Cachexia

Conditions:

Colorectal; Small Lung Cancer

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