BMS‑986490 Solid Tumors Study
Brief Summary
This is a study of BMS-986490 as a monotherapy and in combination with bevacizumab in participants with select advanced solid tumors known to express CEACAM5.
Official Title
A Phase 1/2a, Multicenter, Open‑Label, First in Human Study of BMS‑986490 With or Without Bevacizumab in Advanced Solid Tumors (NCT06730750)
Conditions
Advanced Solid Tumors
Cachexia (AV-380-25-301)
Brief Summary:
This is a randomized, double-blind Phase ⅔ study evaluating the effect of rilogrotug compared to placebo on weight gain and improvement in patient-reported anorexia.
Study Title:
A Randomized, Double-Blind, Phase 2/3 Study of Rilogrotug (AV-380) Versus Placebo in the Treatment of Anorexia and Weight Loss in Patients with Cancer Cachexia
Conditions:
Colorectal; Small Lung Cancer